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Loading...Introduction to CRISPR Gene Editing
When I first started working with CRISPR-Cas9, I was amazed by its potential for gene editing. However, as I delved deeper, I realized that CRISPR-Cas13 was also a player in the field. Last quarter, our team discovered that CRISPR-Cas13 had some unique advantages over CRISPR-Cas9, especially when it came to specificity and off-target effects.
CRISPR-Cas9: The Pioneer in Gene Editing
CRISPR-Cas9 is the most well-known CRISPR system, and for good reason. It's been widely used for gene editing due to its efficiency and relatively simple design. The system consists of two main components: the Cas9 enzyme and a guide RNA (gRNA). The gRNA is designed to bind to a specific sequence of DNA, and the Cas9 enzyme then cuts the DNA at that site, allowing for gene editing.
CRISPR-Cas13: The New Kid on the Block
CRISPR-Cas13, on the other hand, is a more recent discovery.
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